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Abstract One of the frequent musculoskeletal problems is knee pain. The trend of increasing of knee pain among the populations is noted. Therefore, choosing a reliable screening tool with reasonable cost is mandatory. Although MRI is the gold standard imaging modality for knee soft tissue structures, it has been widely abused with its high cost. US is an established modality to image the soft tissue structures of the knee. Our aim is to detect the reliability of US in diagnosing cases with medial knee pain as compared to MRI. Our study included twenty patients with knee pain. Every patient underwent MRI and US examinations independentely and blindly. US is tested in detecting soft tissue structures pathology such as knee effusion, meniscal pathology (tear, degeneration and extrusion), medial collateral ligament,bursitis (Baker’s cyst,pes anserine), intramuscular and subcutaneous heamatoma and osteophytes So we can conclude that: Ultrasound is an effective imaging modality that can be suitable as a screening tool for patients having knee pain. Knee US has reasonable accuracy in detecting collateral ligament and meniscal pathology. US with the advantages of being widely available, lower in cost and with no contraindications should be the first modality of choice in evaluating knee pain. MRI can be reserved for equivocal US results |