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Abstract Antioxidants are man-made or natural substances that may prevent or delay some types oce, damag, 0ne of the harmful effects of oxidative stress’s its role fn inducing olecular damage and disrupting their regular functions specifically for nucleic acidSS pids and proteins. Human body responds to such an undesirable phenomenon by pro ucmg antioxidants through several mechanisms either naturally produced or fromcerta PrfV1H<hFrom,fo°df pPlemen‘s- Externally produced antioxidants are derived I rom certain foods being loaded with antioxidant substances. Exposure to low levels of CuO nanoparticles through food, water, and air is common in industrial areas is a real threat to the health of the general population The toxic effects of CuO NPs, especially at low doses (that are likely in the environment) are poorly recognized. Therefore’ the aim of this study was to address the protective role of green tea extract to relieve toxicity induced by CuO nanoparticles, group I (control) was intraperitoneally injected with carboxy methyl cellulose, group II was orally administered with a dose equal 400 mg/kg of body weight of Green tea. , group III was intraperitoneally injected with a dose equal 2. mg/ go o yweight of CuO-NPs (low dose). |