الفهرس 
DIABETES MELLITUSOnly 14 pages are availabe for public view
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Abstract
SUMMARY The prevalence of gestational diabetes mellitus (GDM), one of the most common metabolic disorders during pregnancy, is increasing worldwide, possibly due to advancing maternal age and rising obesity rates. Women with GDM are also more prone to develop type 2 diabetes mellitus (T2DM) in the future Overweight and obesity in women at reproductive age advances the development of insulin resistance and thereby increases the risk for early deterioration of pregnancy metabolism. Besides its function as an energy storage site, adipose tissue acts as an endocrine organ, secreting proteins that are involved in various physiologic interactions with other organic systems. Adiponectin and leptin are suggested to play a considerable role in the regulation of whole-body glucose homeostasis. 1,5 Anhydroglucitol (1,5 AG) is structurally similar to glucose. It is absorbed mainly from ingested food and is distributed to all organs and tissues. Under normal glycemic conditions, levels of 1,5 AG is constantly maintained through renal filtration followed by reabsorption in the proximal tubule. Clinical studies have also reported 1,5 AG as a short-term postprandial marker for hyperglycemia The work of the present study aimed to predict gestational diabetes by measuring serum adiponectin 1,5 anhydroglucitol during the first trimester. This study was done on fifty pregnant women during the first trimester. Patients divided into two groups