الفهرس 
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Abstract
MicroRNAs (miRNAs) are a class of 18-25 nucleotides, non-coding, regulatory RNAs that inhibit the translation of mRNAs by binding to sites of imperfect complementarity found in (3’UTR) of their affected genes. To date, thousands of miRNA genes have been identified and each miRNA may potentially target many different (ten to hundreds) mRNAs. These genes are mainly involved a variety of biological functions, including post-transcriptional splicing, DNA repair, mRNA maturation and so on, which also play a role in multiple biological processes, such as limb growth, muscle development, cellular immunity. Dysfunction of miRNA pathway is also a potential important contributor to the pathogenesis of major disorders.
The present work was designed to highlight the role of miRNA and their affected genes in regulating of skeletal muscle growth and to enhance production by reducing protein which is the most expensive element in ration and compensate with limiting AAs and synthetic peptides due to high demand of meat in broiler.
The present study divided 216 one day old chicks, (45.5g+0.29) weight into 9 groups for 42 days.
Experiment I: was conducted to study the effects of lowering dietary protein supplementing with limiting AAs (leucine &
The birds were weighed individually at the beginning of each experiment and then body weight recorded every week also feed intake for each group was recorded.