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العنوان
Can Plasma Cholinesterase act as an Adjuvant Prognostic Index in acute Burn Cases? /
الناشر
Faculty of medicine
المؤلف
Mohamed,Yasmine Fikry Mohamed
هيئة الاعداد
باحث / ياسمين فكري محمد محمد
مشرف / أ.د./ أماني السيد عبد الرحمن
مشرف / أ.د./ محمد احمد السيد مصطفي الروبي
مشرف / د./ داليا محمد نبيل ذكي
تاريخ النشر
2020
عدد الصفحات
148 P.:.
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأمراض والطب الشرعي
تاريخ الإجازة
1/1/2020
مكان الإجازة
جامعة عين شمس - كلية الطب - لطب الشرعي والسموم
الفهرس
Only 14 pages are availabe for public view

from 147

from 147

Abstract

Background: The importance of burn prognostic indices lies not only on the prediction of the outcome of an individual patient, but also on the distribution of the patients in comparable groups of severity for therapeutic purposes. Although the realistic prediction of the outcome of an individual patient is the first and main question of patient family, the quantitative measurement of a patient illness using these indices is of great importance for the burn center in deciding its therapeutic policy. The more accurate the index, the more useful it is for the latter purpose for these reasons. Aim: The aim of this study is to assess the potential role of plasma Cholinesterase as an adjuvant prognostic index in acutely burned patients to ascertain malpractice claims. Methods and results: A prospective study that was conducted in The Burn Unit at El Demerdash Hospital. Venous blood samples were collected from each patient under study on the first day of admission, 5th day and the 14th day after admission. on day 1 plasma cholinesterase sensitivity was the highest when it was measured alone, on day 5 and day 14 plasma cholinesterase sensitivity was the highest(100%) when combined with CRP, when combined with albumin and when combined with CRP, albumin collectively . Conclusion: The current study concluded that Plasma cholinesterase can be measured as a prognostic index alone with 100% sensitivity on day 1, 5 and 14 post burn, when it is used as an adjuvant to platelets on day 1 sensitivity is 98%, when it is used as an adjuvant to CRP on day 5 and 14, the sensitivity is 100%, to albumin on day 5, 14, the sensitivity is 100% and when the three parameters (plasma cholinesterase, albumin and CRP) collectively measured the sensitivity is 100%.Recommendations: The present study recommended plasma cholinesterase to be measured alone with sensitivity 100% or adjuvant to albumin, CRP or both with sensitivity 100%.