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العنوان
Database Establishment of Ketogenic Diet Clinic in Ain Shams University Children’s Hospital/
المؤلف
Shokair,Wafaa Mostafa Abdelwahab
هيئة الاعداد
باحث / وفاء مصطفى عبدالوهاب شقير
مشرف / أمنيه فتحى الرشيدى
مشرف / مى فؤاد نصار
مشرف / ياسمين جمال عبده الجندى
تاريخ النشر
2020
عدد الصفحات
158.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
13/2/2020
مكان الإجازة
جامعة عين شمس - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

from 158

from 158

Abstract

ABSTRACT
Background: The Ketogenic Diet (KD) is a high-fat, low-carbohydrate, and adequate-protein diet well-established as treatment option for drug resistant childhood epilepsies. Recent studies have found a significantly positive outcome with the use of the KD for treatment of refractory epilepsy in children and adults.
Objectives: The objective of this study was to design a database system for registration and revision of all patient files in ketogenic diet clinic (Ketoclinic) in Ain Shams University children’s hospital (history, examination, investigations, diagnosis and follow up sheet) from October 2013 till October 2019.
Subject and Methods: It was a descriptive cross-sectional study conducted in the Ketoclinic Ain Shams University Children’s Hospital from the period between October 2017 till October 2019 and involved all patients in the Ketoclinic since its start in 2013.
Results: The number of patients increased from 2013 till 2019 and also the compliance of the patients increased. The record of the Ketoclinic at the end of 2019 were 143 patients, 43 (30%) still following on KD, 80 (56%) stopped the diet, 15 lost (10.5%) and 5 (3.5%) died. We assessed two parameters for the evaluation of the efficacy of KD in our patient; Chalfont severity scale and frequency of the epileptic attacks per day. As regard frequency of convulsions there was decrease after 3 months of KD and more decrease after 24 and 36 months of the diet. On applying Chalfont seizure severity scale on our patients it showed decrease after KD. Concerning lipid profile, there was no difference after KD usage. Weight assessment in our patients showed highly specific increase in the weight and Z score for weight. Also height/length assessment showed increase same as its z-score. Regarding the body mass index (BMI), there was no increase in BMI and in z-score BMI for age.
Conclusion: Registration of the Ketoclinic patients using software program helped us identify epidemiological factor of different group of patient on KD. The Ketoclinic data further proves that KD is an effective line of therapy with significant improvement in the frequency and severity of convulsions in patients with intractable epilepsy and has proved to be tolerable, safe and effective line of therapy for intractable epileptic seizures in children without significant adverse effects on anthropometry or lipid profile of the patients.
Keywords: Database Establishment, Ketogenic Diet