الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Thyroid dysfunctions are common endocrine disorders seen during pregnancy. Overt or subclinical thyroid dysfunction during pregnancy adversely affects maternal and fetal outcomes. Aim of the study: This study was undertaken to know the magnitude of thyroid dysfunctions during pregnancy in our region and to validate the need for early detection of maternal thyroid dysfunctions by antenatal screening. Methods: It was a hospital based prospective study. According to our study criteria, blood samples were collected from consenting pregnant woman during their first antenatal visit and analyzed for TSH level by ultrasensitive method. Free T3 and Free T4 were assayed with TSH level. Results: Among 300 pregnant women studied 90.7% were euthyroid and 9.3% showed thyroid dysfunction, affecting more in the age group 21-30 years. Prevalence of hypothyroidism was 6.6%, presenting as subclinical hypothyroidism (5.3%) and overt hypothyroidism (1.3%). Hyperthyroidism was seen in 2.7% of cases, 2% of them presented subclinically and 0.7% overtly. Conclusion: This study showed 9.3% prevalence of thyroid dysfunction in pregnant women and commonest dysfunction was hypothyroidism in subclinical form. Recommendations: Thyroid dysfunction in pregnancy is associated with adverse pregnancy outcomes; hence, antenatal thyroid screening should be judiciously offered. Prompt detection and corrective treatment with thyroxine can prevent many obstetrical complications and result in the delivery of a healthy baby. Therefore, routine testing with serum TSH is a sufficient and cost-effective screening tool.