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العنوان
Noninvasive laboratory markers as a predictor of esophageal varices in egyptian cirrhotic patients /
المؤلف
Ali, Mohammed Elshokaly Abdelati.
هيئة الاعداد
باحث / محمد الشكلي عبد العاطي علي
مشرف / عادل عواد مصطفي
مشرف / حاتم سمير العجيلي
مناقش / هشام سعد محمد
الموضوع
Esophageal Varices. Liver Disease.
تاريخ النشر
2020.
عدد الصفحات
167 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكبد
تاريخ الإجازة
1/1/2020
مكان الإجازة
جامعة بنها - كلية طب بشري - أمراض الكبد
الفهرس
Only 14 pages are availabe for public view

from 167

from 167

Abstract

Esophageal varices are generally the most common clinical manifestations of portal vein hypertension, and haemorrhagic varicose veins are the most bloody complication of portal vein hypertension. Current criteria in standard tests for assessing portal vein hypertension and esophageal varices are the measurement of the hepatic venous pressure gradient through hepatic venous catheterization and gastroscopy and esophagus. , Respectively, the Fifth Pavino Consensus suggested endoscopic examination of esophageal varices for all cirrhotic patients upon diagnosis. The standard diagnostic tool for esophageal varices is endoscopy. Esophageal varices develop as a result of portal hypertension in patients with chronic liver disease and are found in about 50% of patients with Cirrhosis. The degree of esophageal varices often correlates with the severity of the liver disease. While approximately 85% of individuals with Child-Boc fibrosis have varicose veins, they are only present in 45% of those with Childe-Bo-A cirrhosis.However, less than 50% of cirrhotic patients have varicose veins on an endoscopic examination, and most of them are present. They have small varicose veins with low risk of bleeding. Endoscopy is an interventional technique that is not easily accepted by patients and is expensive so there is clinical demand for a sensitive method for evaluating esophageal varices. Predictions of non-invasive esophageal varices are particularly important in developing countries such as Egypt where it is not easy to perform Endoscopes for a large number of cirrhotic patients Non-interference has become a major goal in liver disease in recent years, as it has been shown that many of the serum markers and imaging methods correlate well with the stage of fibrosis and tend to replace the liver eye, and there is a close relationship between cirrhosis and hypertension of the portal vein And esophageal varices, and many of these methods have been tried for non-invasive evaluation of portal venous hypertension or the presence of esophageal varices. Predictors of non-invasive esophageal varices include platelet count, splenomegaly, splenic diameter, Child’s scale. Bo, right lobe volume of liver, albumin level, and portal vein diameter. These methods are cost-effective, simple and fast, with no additional burden on patients. The Child-Poe Score was first suggested by Child and Turcotte to predict the risks of surgery in patients undergoing CVS surgery for variceal bleeding. Modified by adding prothrombin time or international normalized ratio and removing nutritional status. Child-Poe score has been used extensively to assess the severity of liver dysfunction in clinical work.