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العنوان
The impact of fortify some food products with arabic gum (Sengalia Senegal) on renal oxidative stress in experimental rats /
المؤلف
Allam, Shimaa Mohamed Ahmed Abd-Elmohsen.
هيئة الاعداد
باحث / شيماء محمد أحمد عبدالمحسن علام
مشرف / عفاف هانم محمود رمضان
مشرف / هناء فاروق محمود المهيرى
مناقش / عفاف هانم محمود رمضان
الموضوع
Home Economics. Nutrition and Food Science.
تاريخ النشر
2020.
عدد الصفحات
118 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
اقتصاد منزلي
تاريخ الإجازة
1/1/2020
مكان الإجازة
جامعة المنصورة - كلية التربية النوعية - الاقتصاد المنزلى
الفهرس
Only 14 pages are availabe for public view

from 118

from 118

Abstract

This workaims to study the effect of preparation flat fortified bread (FFB) by replacing 25%,50% and 75% of Arabic gum (AGM) on the chemical composition of the product and its effectiveness on potassium bromate (KBrO3) (100 mg / kg of Body weight) that caused renal toxicity in albino male rats through nutritional indicators, some chemical and biological analyzes of liver and kidney function, antioxidant enzymes and histology of rats kidney used in the experiment. Thirty sex rats (Sprague Dawley Strain) weighing (130 ±10g) were randomly divided into sex groups., each consisting of six rats classified(n=6) ,The first group was kept as negative control group (-ve), while the other five groups were injected with KBrO3 to induce toxicity in various experimental rats. One of those groups was fed on basal diet only and served as positive control group (+ve). The third group was fed on basal diet and treated with flat bread FB (100% WF) control, the fourth, fifth and sixth groups were fed on basal diet containing FFB with AGM (25%, 50% & 75%) respectively. Results revealed that rats consumed FFB with AGM (25%, 50% & 75%) showed significantly increased in FER and weight gain compared with positive group ,biochemical analysis data indicated a significantly decrease at p˂ 0.05 in blood lipids profile (TC, TG and LDL) ,while significantly increased were noticed at p˂ 0.05 in liver function (ALT and AST), and kidney function (urea, uric acid and creatinine) compared to positive group + ve. The previous results were also supported by microscopic examination of the renal tissues of groups infected with renal inflammation and treated with bread supported by different percentages of Arabic gum (25% and 50%). It can be recommended to pay attention for the benificial of AGM in the diet plan for patients to improve the antioxidant status and reduced the levels of Renal Oxidative Stress.