الفهرس 
Introduction & Aim of the WorkOnly 14 pages are availabe for public view
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Abstract
Peyronie’s disease is a localized fibrous scar in the tunica albuginea of the penis resulting in a palpable penile plaque, penile pain on erection, penile curvature and erectile dysfunction.
In this study, sixty-two patients were clinically evaluated for Peyronie’s disease. Age distribution was from 33-72 years, the biggest percentage (38.7%) was from 51-60 years. We found that smoking patients 83%, Diabetes Mellitus 66% and penile trauma 50%.
We found that penile length was from 9.2 to 14.5 cm, degree of penile curvature was from 30o-45o, score of erectile function was from 20 – 25.
Two groups of patients were evaluated, the first one (non-surgical group) included 44 patients, 30 of them treated with oral therapy in the form of Colchicine, L-Carnitine and vitamin E for six months. Improvement of penile bending was 50% and improvement of painful erection 40%. The other 14 patients were candidates for Intralesional injection therapy using Verapamil injection. Improvement of penile bending was 56% and improvement of painful erection 70%.
The second group (Surgical group) included 18 patients, 10 of them were operated upon by plication of the tunica albuginea in the contralateral side of the fibrous plaque, resulting in improvement of penile bending 80%, improvement of painful erection 70% and improvement of erectile function 60%.
The other 8 patients were operated upon by penile prosthesis implantation resulting in improvement of penile bending 100% improvement of painful erection 83% & improvement of erectile function 100%.
Post-operative complications as wound infection & hematoma (only 5 cases) managed successfully by daily dressing & antibiotic coverage.
Post-operative patient’s satisfaction increased gradually by time from 3 to 9 months post-operatively.
We conclude that:
1- Combined oral and intralesional injection therapy are suitable for acute phase of Peyroni’s Disease (from 6-12 months) of discovery.
2- Surgical Treatment is the best choice for the chronic phase of the disease.
3- Many surgical procedures are available for the surgeon to choose among them.
4- Penile Prostheses Implantation is the gold standard maneuver for Peyroni’s Disease associated with erectile dysfunction.
Take a Home Massage
1- Thorough Clinical history and investigations of new cases of Peyronie’s disease.
2- You will not discover until uncover so, meticulous genital examination is a must.
3- Discuss treatment options with the patients to explain advantages and disadvantages of each maneuver.