الفهرس 
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Abstract
In this prospective study, we investigated pretreatment serum albumin and C-Reactive Protein (CRP), a combination of CRP and albumin levels forming inflammatory prognostic score called Glasgow prognostic score (GPS) and it’s correlation with prognosis of patients with ovarian epithelial carcinoma.
A total of 57 newly diagnosed patients with malignant epithelial ovarian carcinoma, presented to Clinical oncology department, Menoufia University and Meet Ghamr Oncology Center, were included in this study. Mean age at diagnosis was 55 years (ranging from 23–80).
Glasgow Prognostic Score (GPS) was suggested to be a prognostic scoring system on the basis of CRP and albumin levels, was a powerful prognostic factor in patients with advanced epithelial ovarian cancer.
In our study we found that high GPS was significantly associated with Age, performance status, elevated Ca125 level, advanced stage, ascites, size of residual tumor after the debulking surgery and platinum sensitivity (P < 0.001). In addition, patients with higher GPS had shorter progression-free survival (PFS; P < 0.001) and overall survival (OS; P = 0.107).
As regards to univariate analysis we found that age, CRP, albumin, GPS, stage, optimal surgery, platinum sensitivity have significant association with progression free survival.
In multivariate analysis of PFS results showed platinum sensitivity is was significantly associated with PFS, so platinum sensitivity is significant independent predictors of PFS.