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Abstract Despite improvement of therapy strategy of chemotherapy was increasing survival rates of ALL patients but also increasing complication during or after chemotherapy. The most common complication during or after chemotherapy is osteonecrosis. Osteonecrosis means reduction or complete loss of blood supply to bone, so the patients had pain in the necrotic area. MRI is the modality of choice for evaluation of osteonecrosis at an early stage especially when results of other imaging modalities are negative or the patient is still asymptomatic. MRI is nearly 100% sensitive and specific for early OS and is, therefore, highly effective for screening. Also, MRI avoids ionizing radiation exposure and can be safely used in pediatric patients especial for those requiring follow up. Our study included 30 patients, 16 of them were males while 14 were females. The age of our selected patients ranged from 4 to 17 years, all of them were in pediatric age group. All patients were subjected to the following: clinical evaluation. Laboratory tests (complete blood count, renal function tests, electrolyte tests, and liver enzyme tests and coagulation profile) and Magnetic resonance imaging (MRI). |