الفهرس 
Seizures OverviewOnly 14 pages are availabe for public view
 |  | from | 82 |  |  |
| | | from | 82 | | |
Abstract
Seizures represent the most common neurologic emergency of childhood
and can be terrifying for patients and families. Although there are a variety of
potential causes for seizures, the common pathophysiology entails abnormal
electrical discharge of neurons; the extent of this aberrant electrical activity and
subsequent manifestation of the seizure may range from subtle, non-convulsive
events to stereotypic movements to dramatic generalized convulsions.
Febrile seizures are the most common form of childhood seizures,
affecting approximately 2–5% of children. Usually occur between 6 months and 5
years of age, with a-peak incidence at 18 months.
Seizures can be either provoked or unprovoked. Provoked seizures occur
in the context of a brain insult and may not recur when the underlying cause is
resolved. Triggers include head trauma, toxins, fever, electrolyte abnormalities,
hypoglycemia, and other causes. Unprovoked seizures may be cryptogenic or may
be the result of a brain malformation, disturbance of neuronal migration, or a
genetic syndrome.
Most seizures will self-resolve, a subset of patients will progress to status
epilepticus and require anticonvulsant medication. Neuronal damage can occur
with prolonged seizure activity, but the timing of damage is complex,
multifactorial, and difficult to predict.
This study aimed to assess clinical characteristics, analysis of etiology and
prognosis in hospitalized children with seizures in Menoufia University.
This study included 100 children, with convulsion admitted to pediatric
department, Menoufia University, were subjected to full history taking, full
clinical examination and lab. Investigations as CBC, electrolytes and blood
culture in addition to neuro imaging EEG (electroencephalography),
Computerized Axilla Tomography scan or magnetic resonance.
Results: 46% males and 54% females, their mean age was 4.8±3.8 years, the
convulsions were generalized in 90% and focal in 10% of patients, the mean
duration of fit was 9.6±8.0 mins, the most common cause of convulsions was
febrile convulsion (53%), followed by epilepsy (31%), then CNS infections (11%) and IEM (5%).
Although febrile seizures are benign, under certain circumstances, febrile
seizures need to be prevented if possible because the seizures cause so much anxiety and worry in the parents.