الفهرس | Only 14 pages are availabe for public view |
Abstract Induction of labor is a widely used intervention on the modern labor and delivery unit. While it follows electronic fetal monitoring and ultrasound in frequency, the use of this procedure has increased 9.5% in 1990 to 20.6 in 2002- 2003. The Bishop Score ,since its description in 1964, remains the gold standard for assessing favorability for induction of labor, However ,the pre induction “favorability “of the cervix as assessed by the Bishop Score is very subjective and several studies have demonstrated a poor predictive value for the outcome of induction especially in women with a low Bishop score. As the supra -vaginal portion of the cervix makes up about 50% of the cervical length and varies from one women to another. This portion of the cervix is difficult to estimate digitally and it makes assessment highly subjective, so Transvaginal ultrasonography measurement of cervical length may be a more objective method for assessing cervical status. Aim of the study to compare between ultrasound measurement of cervical length and detection of IGFBP-1 in cervical secretions in prediction of successful induction of labor after 37 weeks. In this study 140 women 37-42 weeks pregnancy underwent induction of labor due to post date, gestational diabetes and PIH. Using 25micro g misoprostol vaginally. The doses were given at 6 hours interval for maximum of 4 doses. Before induction the attending obstetrician detect IGFBP-1 in cervical secretions by Actim partus test then performed a digital examination of the cervix and noted Bishop Score. Cervical length was then measured by TVUS. And when uterine contractions start external CTG was regularly performed to monitor the condition of the fetus. The mean age was 23.34±4.09 years. The BMI mean was 29.12±2.57kg/M2. The GA mean was 39.85±1.41 weeks. The most common cause of induction was postdate (67 women) followed by PIH (40 women) then gestational diabetes (33 women). 97 pregnant women were delivered vaginally and 43 were delivered by caesarian section. Indications of C.S were mainly due to failed induction (patient received 4 doses of misoprostol 25 microgram with 6 hours interval and no labor pains nor cervical dilatation or effacement were noted ), fetal distress, and failure to progress. The mean age of females delivered vaginally was 23.34±4.13 years while was 23.35±4.05 in those who delivered by CS. The mean BMI of patients delivered vaginally was 29.06±2.51 kg/M 2 while was 29.26±2.70 kg/M 2 in those who delivered by CS. The mean GA of females delivered vaginally was 39.80±1.41 weeks and it was 39.97±1.43 weeks delivered by CS.The mean cervical length measured by TVUS in females delivered vaginally was 24.89±5.48 mm. While it was 26.79±3.06 mm in females delivered CS. The mean Bishop Score in patients delivered vaginally was 6.21±1.45 while it was 4.79±1.45 in those who delivered by C.S. IGFBP-1 was positive in 71females delivered vaginally .and positive in17 females delivered by CS. from the previous data we found a statistically significant positive correlation between cervical length measured by TVUS and detection of IGFBP-1 in cervical secretions by Actim partus test and successful induction of labor after 37 weeks. |