الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
The development of new chemotherapeutic agents for the treatment of cancer is still urgently needed to help ensuring the availability of new drug candidates to feed the preclinical pipeline. This will help to surmount current issues arising from the drawbacks of current drugs such as low efficacy, significant side effects and resistance. In this context, nitrogen containing heterocycles are still an important resource for the discovery of new drugs.
Acridine and its analogues have recently drawn renewed interests and attentions as the seeds of novel medicines. However, side effects, drug resistance and poor availability have caused limitation in clinical use of such heterocyclic core structure and motivated the further structural modification of these compounds. In order to develop novel medicines based on acridine core structure, sufficient amounts of compounds need to be provided for derivatization and biological testing. Such aforementioned facts inspired us to explore an efficient synthetic methodology for some new acridine derivatives and screen their anticancer potency against different cancer cell lines. Towards that end.