الفهرس 
literature reviewOnly 14 pages are availabe for public view
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Abstract
As in the most malignant diseases, early detection of breast cancer is effective for easy treatment enhances patient survival, and reduces the rate of death A metabolomics study for the determination of some candidate metabolomes derived from nucleosides in serum and urine specimens of patients with malignant breast diseases. A simple, reliable, and fast method based on GC/MS was developed to identify three serum and urinary candidate metabolomes: 1-MA, 1-MG, and 8-OHdG. These metabolomes are associated with breast cancer and may be useful for early diagnosis of the disease. These metabolomes had been suggested to be a valuable biomarkers panel for the staging, early detection, diagnosis and treatment monitoring of breast cancer using GC/MS.