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Abstract Preeclampsia is a major obstetrical syndrome classified according to the time of its clinical manifestation as “early preeclampsia” if it occurs prior to 34 weeks of gestation. Early preeclampsia accounts for approximately 10% of the cases and its pathophysiology involves both maternal predisposing factors and disorders of deep placentation. (123) Current prediction models for preeclampsia combine maternal risk factors, Doppler velocimetry of the uterine arteries, and maternal blood proteins.(124) The aim of the work was to find if serum level of protein (C) & protein (S) and uterine artery Doppler show changes during pregnancy that could be used as predictor for preeclampsia. This study included 60 primigravidae women at first and second trimester. The results of this study revealed that protein (C) & protein (S) level and uterine artery Doppler has significantly higher in sever preeclampic women than in mild preeclampic women and normal women. In this study the mean of protein (C) was 35.25% in sever preeclampic patient versus 53.29 % in mild preeclampic patient and 88.79% in normal patient (p. value< 0.001). In this study the mean of protein (S) was 46.0% in sever preeclampic patient versus 56.46% in mild preeclampic patient and 95.56 % in normal patient (p. value< 0.001). Thus level of protein (C) and protein (S) was potentially useful in prediction of preeclampsia. |