الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Curcumin is an active ingredient in turmeric, which is a highly potent, non-toxic, and bioactive agent. It has been used as a home remedy for many diseases for decades. Curcumin is safe and effective in diseases such as autoimmune, cardiac, neoplasm, respiratory, neurodegenerative cancer, and metabolic disorders. The medical properties are due to its anti-inflammation, anti-tumor, antioxidant and immune-enhancing activity. Curcumin has an immunomodulatory effect, such as the regulation of cell reactions and the production of various immune-specific cell forms, including T and B cells and phagocytic cells. Curcumin has the ability to lower TNF-α and IL-6 levels and to modulate a number of different growth factors, transcription factors, cytokines and different enzymes.
Medicinal use of curcumin is restricted by significant problems such as low solubility, instability poor bioavailability, and rapid metabolism.
Nano-curcumin is an enhanced formulation of curcumin with more pharmaceutical effects due to higher distribution in tissues, improved bioavailability, and preservation of curcumin in cells. Once nano-curcumin enters the body, it interacts highly with the innate immune system, resulting in an immune-modulatory response.