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العنوان
Biochemical Study of Autophagy and Apoptosis in Experimental Model of
Neurodegeneration /
المؤلف
Nasef, Nahla Anas Beshir.
هيئة الاعداد
باحث / نهله انس بشير ناصف
مشرف / وفاء محمد ابراهيم
مشرف / سلوى محمد المليجى
مشرف / احمد عبد الحكيم عبدالله
مشرف / ولاء عرفه كشك
الموضوع
Medical Biochemistry.
تاريخ النشر
2019.
عدد الصفحات
p 206. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الكيمياء الحيوية (الطبية)
تاريخ الإجازة
1/1/2019
مكان الإجازة
جامعة طنطا - كلية الطب - كيمياء الحيويه
الفهرس
Only 14 pages are availabe for public view

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Abstract

Neurodegeneration is a common terminal pathway present in aging and
neurodegenerative diseases.Neurodegenerative disorders like Alzheimer’s disease and Parkinson’s disease are common causes of increasing morbidity and mortality worldwide. Multiple theories have been driven to establish the concepts about neurodegenerative diseases and their underlying causes.Misfolded protein aggregation, oxidative stress,inflammation, mitochondrial
deficits, trophic factor loss, and eventually cell death are considered to be the major underlying mechanisms. Alcohol, a sedative agent with
neurodegenerative properties, induces oxidative stress, apoptosis and neuroinflammation so it is a good agent for the induction of experimental neurodegeneration.