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Abstract This prospective study conducted on 20 patients in whom fixation with pedicular screw and rods or neural decompression accordingly using Paraspinal Wiltse approach. Through this approach, a one-level or a multilevel fusion can be performed; leaving the supraspinous and interspinous ligaments intact. Its uses for removing a far-lateral disc herniation, decompressing a far-out syndrome, and inserting pedicle screws, as well as for spinal canal decompression have been well described. As a muscle-splitting approach through the sacrospinalis muscle and between the multifidus and longissimus, The Wiltse approach theoretically lessens tissue destruction and blood loss and improve postoperative pain. With time, the approach evolved to be applicable to multiple indications with a growing number of proposed advantages, including the facilitation of two surgeons working concurrently, more direct pedicle screw insertion trajectories, easier decompression of far lateral disc herniation, and a surgical trajectory that enables decompression of the contralateral canal. In our study there were 20 patients 10 males and 10 females with mean age 47.5 ± 8.14 with spondylolisthesis, disk prolapse, disc prolapse with old fixation L2, and pedicle screw malposition. 12 patients were primary operated and 8 patients were revision. 11 cases were one level and 9 cases were two levels with operative time mean 107 |