الفهرس | Only 14 pages are availabe for public view |
Abstract Contrast-induced nephropathy is a potentially avoidable complication caused during procedures involving the use of radiographic contrast media, All subjects, especially at high risk should be subjected to available preventive protocols prior to and after such procedures. The current study included 73 patients both elective and emergency PCI with E-GFR < 60 ml/kg/1.73 m i.e moderate to severe kidney impairment . The current study was aiming to asses outcome of low dose contrast protocol in chronic kidney disease patients and to asses safe margin for contrast use in these patients. All the patients were subjected to full history taking with special emphasis on the known predisposing factors for CIN, thorough clinical examination, patients were divided into 3 groups according CV/E-GFR Primary or elective PCI were performed by an interventionalist according to standard clinical practice, an echocardiographic evaluation was done to all patients, serum creatinine was measured at the time of admission (just before primary or elective PCI), every day for the following three days in the CCU as well as pre hydration at rate 1 ml/kg/h. The current study found that contrast-induced nephropathy had not occurred in group A i.e low dose contrast 0 % , while CIN occurred in group B 11.5% and group C 35% . Regarding dialysis , it was 0 , 11.5 ,26 % respectively and death 0, 11.5 ,17 % respectively. |