الفهرس 
Anatomy of HeartOnly 14 pages are availabe for public view
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Abstract
: Arrhythmia, postoperative pain and agitation are a common complication after heart surgery and is a major source of morbidity and mortality. Aims: This study aimed to study the effect of magnesium sulfate (MgSO4) for reduction of postcardiac surgery arrhythmia, postoperative pain and agitation. Setting and Design: This study is performed in the cardiac operating room and Intensive Care Unit of EL-Fayoum university hospital and national heart institute (EGYPT) between December 1, 2017, and July 30, 2018. This study is a double-blind, randomized controlled trial. Materials and Methods: In group 1 (group magnesium [Mg]), 70 patients received 30 mg/kg MgSO4 in 500 cc normal saline and in group 2 (group control), 70 patients received 500 cc normal saline alone. Statistical Analysis: Data entry, processing and statistical analysis was carried out using MedCalc ver. 15.8. (MedCalc, Ostend, Belgium). Tests of significance (Mann-Whitney’s, Chi square, Friedman’s, factorial ANOVA, logistic and multiple regression analysis, and ROC Curve analysis) were used. Results: Comparative study between the 2 groups revealed; significant decrease in arrhythmia events in Mg group; compared to control group; with significant statistical difference (p = 0.023). The 2 groups showed marked decrease in VAS scores more in Mg group; compared to control group; during the serial measurements. Comparative study between the 2 groups revealed non-significant difference as regards RASS score (p > 0.05).Conclusion: Mg significantly decreases the incidence of all type of postcardiac surgery arrhythmia and decrease the severity of postoperative pain and agitation.