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Abstract Extracorporeal membrane oxygenation (ECMO) which is also called Extracorporeal Life Support (ECLS), Depending on its configuration, it could be venovenous (VV) or venoarterial (VA), it is used to provide respiratory support, circulatory support, or both. ECMO is a bridge treatment which buys time with adequate tissue perfusion waiting for healing of the natural organs, intervention, surgery or transplantation. Currently, the decision to initiate ECMO depends on pulmonary injury scores which evaluate the severity of respiratory failure, such as Murray’s acute lung injury score and the oxygenation index. A Murray score was used for enrollment and randomization in the ‘‘Conventional ventilation versus ECMO for Severe Adult Respiratory failure’’ (CESAR) Trial, as it can identify severely hypoxemic patients failing protective mechanical ventilation with an estimated mortality risk more than 50 % in comparison to conventional treatment. Thus, with the increasing use of ECMO support, risk factors of death among ECMO patients should be intensively defined to predict successful weaning before initiation of ECMO therapy, this will institutions to appropriately allocate resources and estimate mortality outcomes. For this reason Predictive mortality scores have been recently developed Respiratory ECMO Survival Prediction (RESP) score is one of these scores which has been developed in 2014 to predict mortality after initiation of VV ECMO therapy. It consists of 12 items and the score ranges from -22 to 15. RESP score showed good prediction of survival for patient treated with VV-ECMO. |