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العنوان
Role of Botulinum toxin injection in non allergic non infectious chronic rhinosinusitis
A systematic review/
المؤلف
Hussein,Islam Mohamed Naguib Mahmoud
هيئة الاعداد
باحث / إسلام محمد نجيب محمود حسين
مشرف / أسامه ابراهيم منصور
مشرف / طارق عبد الحميد حمدي
مشرف / أحمد نبيل عبد الحميد
تاريخ النشر
2018
عدد الصفحات
65.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الحنجرة
تاريخ الإجازة
1/1/2018
مكان الإجازة
جامعة عين شمس - كلية الطب - Otolaryngology head and neck surgery
الفهرس
Only 14 pages are availabe for public view

from 65

from 65

Abstract

R
hinitis is defined as inflammation of the membranes lining the nose, characterized by nasal symptoms including itching, rhinorrhea and nasal congestion. Rhinitis represents a global health problem affecting between 10% and 25% of the world population.
Rhinitis can be classified into Allergic, infective and NANIR.
The most common form of nonallergic rhinitis is the idiopathic condition also known as vasomotor rhinitis. Individuals categorized as such are those who not only lack conventional evidence of allergic disease but are also devoid of any evidence of sinusitis/nasal polyposis, anatomic abnormalities, or a known infection.
The first-line treatment for VMR is medical therapy in the form of topical corticosteroid and topical antihistamine sprays (which are indicated for NAR as well as AR). Ipratropium bromide (0.03%) is the only topical anticholinergic approved for treatment of NAR with no systemic side effects except for occasional dryness and epistaxis.
Topical capsaicin has been shown to be an efficacious treatment for NAR based on its modulating effects on C-fibers, but because of its irritant qualities, its use is often limited by patient intolerance, there are no oral antihistamines or anticholinergics currently approved for NAR.
BTX is a new postulated modality of treatment for NANIR, It provides the parasympathetic blockade in intrinsic rhinitis when injected into the nose