الفهرس | Only 14 pages are availabe for public view |
Abstract The most common sarcomas in children include osteosarcoma, Ewing sarcoma, and rhabdomyosarcoma. Pediatric sarcomas most commonly metastasize to the lungs or bone, and as a result, at diagnosis, a full staging evaluation should include a thorough evaluation of the primary tumor with MRI or CT scan, anon contrast chest CT to evaluate for pulmonary metastases, and a bone scan via 99m technetium methylene diphosphonate bone scintigraphy to detect osseous metastases. Ewing sarcoma and rhabdomyosarcoma can also metastasize to the bone marrow, so current treatment protocols require bilateral bone marrow biopsies and aspirates following diagnosis. The aim of this work was to assess the role of PET/CT in management of pediatric sarcoma. The present work included 40 patients with confirmed pathological diagnosis of osseous and soft tissue sarcoma. Out of which 26 patents with history of initial diagnosis of sarcoma and presented to our department aiming for initial staging of the disease. While the other 14 patients presented to us with previous diagnosis and management of different types of sarcomas aiming to assess the presence of recurrence. Out of the 26 patients who came for initial staging, 18 patients presented to us during the time of research for follow up imaging studies for assessment of response to chemotherapy before performing surgical procedures. PET/CT examination was performed to the all 40 patients with 18 patients as we explained did follow up PET/CT during the course of disease in the postchemotherapy preoperative period, so the total number of PET/CT scans were 58 examinations. |