الفهرس 
Nephrotic syndromeOnly 14 pages are availabe for public view
 |  | from | 162 |  |  |
| | | from | 162 | | |
Abstract
The human kidney functions as a key regulator of water balance, acid–base
homeostasis, maintenance of electrolytes, and waste excretion. Kidney function is
best measured as glomerular filtration rate. The presentation of renal diseases may
be nonspecific with paucity of symptoms and signs. Manifestations of renal disease
may be vague, nonspecific, and subtle and may be related to other systems like
gastrointestinal or nervous system or other systems. To narrow the differential
diagnosis, it is necessary to first determine whether the disease is acute, subacute,
or chronic on presentation. The next question concerns which segment or
component of the renal anatomy is involved. This is subdivided into prerenal,
postrenal, or renal. Renal involvement is further subdivided into vascular,
glomerular, or tubulointerstitial disease depending on which segment is involved.
This work aimed to study the epidemiology of renal diseases in pediatric patients
in Menoufia University hospitals.
This cross-sectional observational study was conducted in the pediatric
nephrology unit of Menoufia university hospital starting from 1/10/2018 to
1/4/2019 enrolling patients from our hemodialysis unit, outpatient clinic &
inpatient wards. The studied patients were divided into groups & each group was
studied separately.
Our study included 170 patients with nephrotic syndrome. 76.5% of patients
showed response to steroids, while 23.5% were steroid resistant. 29.4% of patients
were steroid dependent, 7.1% of patients were infrequent relapsers, 1.2% of
patients were frequent relapsers, 10.6% patients were non-relapsers that came for
routine follow-up visits & 28.2% of patients had 1st presentation NS. MCD was the
main pathology found in 69% of biopsies. 40% of SDNS patients showed
remission on MMF, 24% showed remission on oral steroids, 16% of patients