الفهرس 
Introduction& Aim Of The WorkOnly 14 pages are availabe for public view
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Abstract
The aim of the present study was designed to evaluate the morphological ,biochemical and ultrastructural changes in the testes,ovaries and liversof mothers rats and their 14 old age neonates by light and transmission electron microscopy.
In our study female rats were dosed orally with distal water and 0.5, 1.7, and 6.0 mg Se/kg bw/day as (10 - 45) nm SeNPs, for 14 old age neonates. At doses of 1.7 and 6.0 mg Se/kg bw/ day, a lowering in body weight gain as compared with control group. Decrease in Glutathione peroxidase of moderate dose and high dose groups due to increase reactive oxygen species in body tissues. There was increase in oxidative status of Low Dose group comparing to control group. There were no histological changes in the livers, ovaries and testes of Low Dose group and histopathological changes of moderate dose and high dose groups. The toxicity of Selenium Nanoparticles on oxidation status and ultrastructure of ovaries and testes did not occur at low levels 0.5 mg Se/kg but appear with degrees of changes at high level Se NPs (1.7 – 6.0 mg Se/kg).
Our results suggest that Se NPs were not toxic at supra-nutritional levels and can be a positive effect on both neonate rats health at a dose of 0.5 μg Se/kg-bw and in mother rats growth, whereas the chronic toxicity will be induced by more than 1.7 μg Se/kg-bw.