الفهرس 
Vitamin D and Cardiovascular DiseaseOnly 14 pages are availabe for public view
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Abstract
Background: Hypertension is currently deemed an intractable health problem. In addition, hypertension leads to a serious list of cardiovascular issues, such as myocardial infarction, cerebral stroke, congestive heart failure, peripheral vascular disorders and kidney diseases .Vitamin D deficiency is also prevalent in the general population. In addition, 25(OH) D levels correlate inversely with coronary calcification, an indicator of atherosclerosis, and a precursor of CV events.
Objective:
The main aim of the study was to measure serum 25-hydroxy vitamin D in patients with hypertension comparing the results with apparently healthy control subjects.
Methods:
A total of 93 subjects were included in the study: 66 patients diagnosed with hypertension and 27 age and sex matched apparently health control subjects. They were compared regarding serum 25-OHD. Blood pressure was measured using standard method. Systolic and diastolic blood pressure more than 140 mmHg and 90 mmHg respectively were considered as HTN. The serum levels of 25-OHD were measured after obtaining an informed written consent from the study subjects and taking their blood pressure under standard conditions.
Results:
Serum vitamin D levels were significantly different between the study groups in which lower results were reported in patients with hypertension (14.38 ± 5.56ng/ml) compared to the apparently healthy control subjects (25.92 ± 8.86ng/ml) (p value<0.001).
Conclusion:
It can be concluded that there is a mild positive effect of vitamin D deficiency on HTN as in our study, serum 25-OHD was significantly lower in hypertensive group than the control one.