الفهرس 
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Abstract
This study aims to the synthesis of copper complexes of
2,3-dihydroxy benzaldehyde thiosemicarbazone (3a,b), followed by evaluating for their in vitro and in vivo anticancer agent. The compounds (3a & 3b) exhibited a significant anticancer activity towards MCF-7, HEPG2 and PC3 cancer cell lines. In vivo study of, (3a & 3b) compounds revealed a significant anticancer activity towards Ehrlich ascites carcinoma (EAC) cells by significant reduction of its volume and the cell count in treated groups (p<0.001); respectively, compared to the positive control group. The synthesized compounds have potent antioxidant activity and good inducer for apoptosis.