الفهرس 
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Abstract
Aim of work:
We aim to show predictors of mortality for the cases on MV and prognosis of the cases.
Patient and methods:
Design: Prospective analytical study.
Setting: Neonatal Intensive Care Unit (NICU) - Minia University Hospital for gynecology, obstetrics and pediatrics.
Participants: All neonates with respiratory distress admitted to Neonatal Intensive Care Unit (NICU) Minia University Hospital from February 2018 to February 2019
Intervention:
In February 2018 a strategy introduced to understand factors associated with use of ventilators, outcome, complications and duration of ventilation among neonates admitted in Minia neonatal ICU.
Demographic data and laboratory data collected, recorded and analyzed for neonates on MV during study term.
Inclusion criteria:
All the neonates who mechanically ventilated during the study period was included in study.
Exclusion criteria:
We excluded the neonates with surgical congenital malformations, neonates ventilated for surgical causes and those who left the hospital against medical advice.
Outcome measures:
Data regarding clinical outcomes included:
1-Complications as:
• Air leaks (pneumothorax or pulmonary interstitial emphysema (PIE)).
• Bronchopulmonary dysplasia (BPD) (oxygen dependency beyond 28 days).
• Sepsis and shock
2- Duration of weaning/ventilation.
3-Mortality.
Results:
• The percentage of cases survived were (23%) and died cases were (77%).
• Male cases on MV were (64.3%) while female cases were (35.7%). Male cases showed higher rate of mortality (66.0%), compared to females (34.0%).
• Low birth weight <2.5 kg: outcome is poor for VLBW and ELBW than NBW and LBW.
• Small gestational age: below 34 weeks GA showed higher mortality.
• RDS were the most common cause for usage of MV.
• Initial thrombocytopenia, high CRP level and anemia were common in cases died.
• Initial severe acidosis PH ≤7.1 in ABG was found in died group.
• In MV settings with initial high Fio2 and PEEP were more in died group.
• Sepsis, shock and pulmonary hemorrhage were most common complications and both are associated with higher risk for mortality than other complications.