الفهرس 
Aim of the workOnly 14 pages are availabe for public view
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Abstract
Anisometropia is an interocular difference in refraction, is an
important condition in children as it can lead to significant visual
problems as impaired stereopsis, amblyopia, and strabimus. It is
characterized as myopic, hypermetropic, and astigmatic.
The optical coherence tomography (OCT) is a non-invasive
optical imaging technique which is the optical analogue of ultrasound
imaging, which provides high-resolution cross-sectional images of the
retina, optic nerve head and retinal nerve fiber layer thickness that can
be qualitatively and quantitatively evaluated.
This study done at the ophthalmology department at the
Menoufia university hospital aimed to evaluate whether there is a
difference in central macular thickness (CMT) and peripapillary
retinal nerve fiber layer (RNFL) thickness between the two eyes of
individuals having anisometropia more than 3 diopter (D) using
spectral domain optical coherence tomography (OCT).
One hundred eighty patients were included in the study with
either myopic anisometropia, either astigmatic anisometropia, and
with hypermetropic anisometropia. All the patients had anisometropia
of more than 3 D between the two eyes. Any patient with history of
previous ocular surgery, Corneal opacity, Nystagmus, Retinal
pathology as diabetic retinopathy, Glaucoma and Cataract was
excluded.
Detailed ophthalmological examination was done for every
patient including detailed history, cycloplegic refraction, best
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Summary
corrected visual acuity using decimal scale, sit lamp examination of
anterior segment, cover-uncover test with extraocular movements
examination, intraocular pressure measured by Goldman applanation
tonometry and biomicroscopic fundus examination using +78 diopter
lens volk. Axial length was measured. Peripapillary RNFL and CMT
was measured using spectral domain OCT then statistical analysis was
done.
This study showed that the worse eyes had significantly lower
mean values of superior RNFL thickness than the fellow eyes in
astigmatic anisometropic patients. Also, the worse eyes had
significantly higher mean values of temporal RNFL thickness than the
fellow eyes in hypermetropic anisometropic patients. But no
correlation between myopic anisometropic and RNFL thickness and
no significant difference in mean central macular thickness in any
group. Interocular acuity difference was significant in myopic
anisometropia and in hypermetropic anisometropia but in astigmatic
anisometropia was insignificant. There was no statistically significant
difference in age, sex and the axial length of the worse and better eye
in all types of anisometropia.