الفهرس 
DyspepsiaOnly 14 pages are availabe for public view
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Abstract
Dyspepsia is a very common upper gastrointestinal problem and its causes may be functional or organic in nature like NSAIDS or H.pylori infection and GERD . also ,H.pylori prevalence is high in dyspeptic patients and because it was considered carcinogenic organism and cause a wide spectrum of health problems (like peptic ulcers, gastric lymphoma ,anemia and thrombothytopenia etc .) . in this study 100 dyspeptic patients investigated for H.pylori prevalence using UGIE to obtain biopsy for histopathology and urease test and revealed 90% and 89% prevalence of H.pylori respectively. also H.pylori stool Ag revealed 87%prevalence in these 100 patients and only urease positive patients ( 89 patients out of 100 dyspeptic patients) included in the study . In this study group female 50 (56.2%) male 39 (43.8%) and before treatment there laboratory investigations revealed anemia in 13 (14.6%) and thrombothytopenia in7 (7.9%) elevated liver enzymes in 6( 6.7%) elevated bilirubin in 2 (2.2%) and elevated FPS 3 (3.4%).these 89 patient evaluated after taking load regimen( omeprazole 40mg once daily ,nitazoxanide 500 mg twice daily ,levofloxacine 250 mg once daily and doxycycline 100 mg once daily ) but with extended duration (14 days ) and after 4weeks from end of treatment H.pylori stool Ag test revealed eradication of H.pylori in 79 (88.8%) and failure in 10 (11.2%) and there laboratory investigations after treatment revealed increase in HB concentration and number of anemic patients decreased to became 8 (9%) , also increased platelets number in some patients reduced thrombocytopenic patients to became 4 (4.5%) , increase in elevated liver enzymes patients in 16 (18%) and elevated bilirubin in 9(10.1%) patients and elevated FPS patiens were the same 3 (3.4%) and as a conclusion load regimen was effective and safe with some few advirse effects in treatment of H.pylori infected patients.
key words : H.pylori ,load regimen.