الفهرس 
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Abstract
The aim of the present study was conducted to evaluate the protective effects of Moringa and vitamin E in rats against Cisplatin adverse effects, These effects regards to some parameters as liver and kidney functions, antioxidant activity, as well as histopathological findings.
Expermental protocol: Eighty albino rats weighting at the beginning of the experiment 180 ± 20 gm. Animals were housed in cages at 25 ± 0.5º C. The animals were divided into 4 main groups:
At the end of experimental (12 hrs. after the last dose) rats were sacrificed and the samples were collected:
- effects on liver functions. - effects on kidney functions.
- effects on antioxidant activity.
Tissue samples also were taken from liver and kidney of rats under study to assess histopathological effects of drugs in the 21st days .
A) Effects on Liver functions:
1- Aspartate aminotransferase.
2- Alanine transaminase.
3- Alkaline phosphatase.
4- Total protein.
5- Albumin.
B-Effects on kidney functions:
1- Urea.
2- Creatinine.
C- Effects on oxidant/ antioxidant activity:
1- Catalase. 2- Glutathione Peroxidase. 3- Malondialdhyde.
C- Histopathological effects:
group 1: Control group 2: Cisplatin
Severe cystic dilatation of the proximal and distal tubules in cortex and collected tubules in medulla were detected.
group 3: Cisplatin +Vit. E group 4: Cisplatin +Moringa.