الفهرس 
Gastroesophageal reflux diseaseOnly 14 pages are availabe for public view
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Abstract
Background: Laryngopharyngeal reflux (LPR) is the retrograde movement of gastric contents (acid and pepsin) into the laryngopharynx leading to symptoms in the larynx or the hypopharynx. Typical Laryngopharyngeal reflux symptoms include dysphonia, hoarseness, dysphagia, globus pharyngeus, chronic cough chronic throat clearing, excessive throat mucus, sialorrhea, sensation of postnasal drainage, dysgeusia, halitosis, throat pain and heart burn. Aim of the work: to assess the value of Pepsin measurement in the sputum/saliva as a non-invasive method for diagnosing Laryngopharyngeal reflux (LPR). The present study was performed on fifty patients and divided into 2 groups, group A include twenty five patients with LPR symptoms and group B include Twenty five apparent healthy persons act as control group with their ages ranged from 20-60 years or any other abnormalities in the upper gastrointestinal tract. Results: There is significance difference between the salivary pepsin value and the GERD grade as the salivary pepsin value increases with the increase of the GERD grade. There is a significant correlation between laryngoscopic findings and Salivary Pepsin level as the P value for all are < 0.05. There is a significant correlation between other endoscopic findings as duodenitis and gastritis and Salivary Pepsin level as the P value for all are < 0.05. Conclusion: ********.