الفهرس 
MelasmaOnly 14 pages are availabe for public view
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Abstract
Forty female patients with facial melasma were treated with intradermal injection of Tranexamic acid in right side of the face and topical Tranexamic acid application after fractional carbon dioxide laser laser on the left side. All cases were assessed by modified Melasma Area and Severity Index score, photos before and after treatment and patient and physician satisfaction scoring.
Results: Modified Melasma Area and Severity Index score of injected side decreased from12±4.4 to 9.6±3.8 and modified Melasma Area and Severity Index score of laser side decreased from11.8±4.8 to 9.7±4.2. There was no statistically significant difference with p-value >0.05 between two sides regarding patient and physician satisfaction.
Conclusion: In conclusion, Tranexamic acid is considered an effective treatment for melasma, there was no difference between intradermal injection of Tranexamic acid and usage of carbon dioxide laser as a route of delivery to topical Tranexamic acid. However, further studies on larger scales are required