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العنوان
Synthesis and reactions of some new pyrazoline derivatives and related compounds /
المؤلف
AbdEl-Samie, Abeer Refaat AboEl-Asrar.
هيئة الاعداد
باحث / عبير رفعت ابو الاسرار عبد السميع
مشرف / السيد محمد عفصه
مشرف / ابراهيم عبد الجليل عبد السميع
مشرف / سها مصطفى عبد المجيد
الموضوع
Chemistry, Organic. Pyrazoles.
تاريخ النشر
2019.
عدد الصفحات
170 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكيمياء
تاريخ الإجازة
1/1/2019
مكان الإجازة
جامعة المنصورة - كلية العلوم - الكيمياء
الفهرس
Only 14 pages are availabe for public view

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Abstract

The work presented in this thesis has emphasized on the synthesis and reactions of some new pyrazoline derivatives, particularly, for the synthesis of some new 4-triazeno-antipyrine starting from 4-aminoantipyrine (4-amino-2,3-dimethyl-1-phenyl-5-pyrazolone) as a key starting compound. The chemistry and pharmacological activity of pyrazoline derivatives received considerable interest due to their wide range of biological and pharmacological activities. A variety of compounds having a 5-pyrazolone moiety as a structural unit, have been synthesized and studied, with interest centered on their potential pharmaceutical activity. Accordingly, the present study has focused on the synthesis of some new 4-triazeno-antipyrines, and polyaza compounds such 1,5-hexaazadienes, 1,4-pentaazadienes and tetraazenes incorporating Antipyrine Moiety. The new products might possess considerable synthetic and pharmaceutical interest.T he material presented in this thesis is separated into two main parts. PART 1: Synthesis of Some New 4-Triazeno-antipyrines and Related CompoundsPART 2: Coupling of 4-Antipyrinyldiazonium chloride with Hydrazine, Hydrazones and Hydrazides