الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Nutritional status is commonly affected in patients with head and neck squamous cell carcinoma (HNSCC). Pre-treatment nutritional status has been suggested to impact treatment outcome. We designed this study to test whether some nutritional parameters, namely BMI, serum hemoglobin and serum albumin, obtained before radiotherapy could predict survival and locoregional control.
We adopted a retrospective study which included patients with pathologically proven HNSCC undergoing definitive RT at our center, Alexandria Clinical Oncology Department (ACOD), during the period from January 1, 2005 to December 31, 2015. The effect of pre-RT BMI, serum hemoglobin and serum albumin on overall survival and locoregional disease control were evaluated.
215 patients met our inclusion criteria and were enrolled for analysis. In our study, 31 (14.4%) were female and 184 (85.6%) were male patients. Their mean age was 57.21 (+/- 9.7). Laryngeal SCC represented most of cases with 84 (39.06%) patients followed by oropharyngeal SCC with 69 (32.1%) patients. stage III and IVA represented most of the cases with thirty-two percent (32%) and forty-three percent (43.7%) of the patients respectively.