الفهرس | Only 14 pages are availabe for public view |
Abstract Background: There is a close relationship between CKD and increased risk for cardiovascular disease: major cardiac events actually represent almost 50% of the causes of death in CKD patients. Aim of Work: to evaluate changes in cardiac structure and function among pre-dialysis CKD patients without heart failure and to assess the possible relationship between these changes and clinical and laboratory data. Patients and methods: This cross sectional study included 60 clinically stable adult patients with various stages of chronic kidney disease (CKD) not yet undergoing dialysis. Patients were recruited from Nephrology Outpatient Clinic of Kobery Alkoba Military Hospital after obtaining their informed consent to participate in the study. Results: There is increased risk of cardiovascular disease in patients with various stages of CKD. Echocardiography is the best tool to study cardiovascular structure and function . Echocardiography can detect early systolic and diastolic dysfunction caused by kidney dysfunction . There is a high prevalence of hypertension in our patients. Hypertension is associated with increased cardiovascular risk in CKD. Proteinuria is important risk factor for cardiac dysfunction. Hypertension and proteinuria must be adjustably controlled to avoid cardiac complication. Conclusion: There is a strong evidence that cardiac function and structure get worsen as the kidney function decline as shown in our study. |