الفهرس | Only 14 pages are availabe for public view |
Abstract Pre-eclampsia is a common disorder of pregnancy, and a major cause of maternal and fetal morbidity and mortality. Today, most obstetricians recognize pre-eclampsia as a complex syndrome. The degree of hypertension and proteinuria are poor prognostic factors for maternal and fetal outcome and better diagnostic and prognostic markers are needed. In pre-eclampsia, maternal plasma levels of cystatin C and beta 2 microglobulins are increased, secondary to renal impairment. The plasma level of cystatin C level has been reported to have a better diagnostic performance for diagnosing pre-eclampsia compared to the plasma levels of urate and creatinine, has been suggested as a complement to serum urate for diagnosing and monitoring pre-eclampsia in the clinical setting. The diagnostic performances of the plasma levels of beta 2 microglobulins for diagnosing pre-eclampsia have not been studied previously. The present study aimed to study the plasma levels of β-2-microglobulin and cystatin C in pre-eclampsia & estimation and correlation of these 2 proteins levels in: d. Normal third trimester pregnancy level to gestational age. e. To the severity of pre-eclampsia. f. To the complications of pre-eclampsia. A prospective case control study was carried out on 20 women diagnosed as pre-eclampsia as well as 20 healthy pregnant women. All patients attended to Obstetrics and Gynecology Department, outpatient clinic Menoufia University Hospital, Menoufia Governorate and Suez insurance hospital, Suez Governorate. During the study period from December 2016 to November 2017. Summary 67 All study patients |