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العنوان
The role of Endovascular Embolization in the Curative Treatment of Brain Low Grade Arteriovenous Malformation /
المؤلف
El-kordy, Alaa Mohammed El-Sawy Ali.
هيئة الاعداد
باحث / علاء محمد الصاوى على الكردى
مشرف / حسن جمال الدين نصار
مناقش / وائل احمد فاضل
مناقش / تامر حسن شحاتة
الموضوع
Neurology. Neuropsychiatry.
تاريخ النشر
2019.
عدد الصفحات
160 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب النفسي والصحة العقلية
تاريخ الإجازة
18/8/2019
مكان الإجازة
جامعة طنطا - كلية الطب - Neurology
الفهرس
Only 14 pages are availabe for public view

from 208

from 208

Abstract

In this study 63 patients with low grade brain AVMs were treated with endovascular embolization alone or as adjuvant therapy before microsurgery or radiosurgery. All patients were followed at 6 and 12 months by DSA. All procedures were performed under general anesthesia and via the trans-femoral approach. After sheath placement, heparin was given to maintain the activated clotting time at 2 to 3 times the baseline throughout the procedure. Next, a proper (6 F) guiding catheter was placed in the distal internal carotid artery or vertebral artery. Subsequently, the AVMs have been treated with endovascular embolization. All detailed data, such as location, SM grade, number of feeders, drainers, presence of a venous varix, number of pedicles embolized, embolizing material, number of embolization sessions and treatment results and complications, have been be recorded. Arrangements were made for all patients to be evaluated at discharge and 30 d (±7 d) post-treatment by clinic visits. Postoperative DSA follow-up is required after 6 ms (±30 d) and 12 ms (±30 d). The angiographic results will be classified into 2 categories when compared with the immediate degree of embolization: 1) Cured or completely occluded; 2) Not cured or partially occluded. 1- from the 63 patients males were 42 (66.7%); females were 21 (33.3%). 2- Hemorrhagic onset was more common in infratentorial AVMs, nidal size ≤ 3 cm, deep venous drainage, single draining vein and the presence of a co-existing aneurysm. - 3- No statistically significant relationship between the variables related to the age, gender, side of the lesion, eloquence of brain areas around the AVMs, SM grading, the presence of a venous varix and the hemorrhagic presentation. 4- Periprocedural complications occurred in 10 patients (16%). 5- Incidence of complications is higher in NBCA treated group, higher number of embolization sessions and with higher number of pedicles embolized. 6- In this study, immediate angiographic results postembolization had shown complete occlusion of 15 from 63 AVMs (24%). Follow up angiographic results at 6 and 12 months after completion of therapeutic strategy with microsurgery or GK radiosurgery has shown complete angiographic cure in 61 from 63 AVMs (97%). 7- Regarding the clinical outcome there are clinical improvement and decrease in mRS in all patients except three patients due to periprocedural complication of the treatment with two mRS 2 and one mRS 3.