الفهرس 
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Abstract
Early diagnosis of avian aspergillosis is critically required to decrease
morbidity and mortality particularly in vulnerable one-day old chicks since
diagnosis of aspergillosis can prove to be a difficult challenge for the avian
veterinarian. Hence, the present study was designed to determine whether
measuring the relative expression of cytokines IL 10, IL 17, IFN γ in lung
homogenates and in PBMNCs of experimentally infected chicks is
significant in the diagnosis of avian aspergillosis.
from a total number of 200 lungs and air sacs samples including 160
chicks and 40 ducks suspected to have avian aspergillosis, A. fumigatus
was the only species isolated (90%). Mortality percent among the affected
birds in different outbreaks was 80-90%. Post-mortem examination
revealed nodules of varied size on lungs and air sacs.
Histopathological examination of lung tissue in chickens and ducks showed
multiple nodules occupying and replacing most of the primary and
secondary bronchioles. Liver sections in chickens showed unspecific
reactions. Each of these nodules formed from central caseated materials
entrapping variable number of fungal hyphae and spores. The surrounding
pulmonary tissue revealed intense vascular, interstitial and alveolar
changes.