الفهرس 
Neonatal sepsisOnly 14 pages are availabe for public view
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Abstract
Background: Neonatal sepsis remains a challenge for neonatal care
providers.
Aim: This work was aiming to measure red cell distribution width percent
(RDW %) as a marker for neonatal sepsis and to correlate it with other
indicators and with a simple clinical scoring system for neonatal sepsis
(Griffin score).
Methods: This case control study was carried out at neonatal intensive care
unit at Fayoum University Hospital. Ethical Research Committee Approval
and written consents were obtained from parents of the neonates 30 neonatal
sepsis cases and 30 normal controls. Neonates were subjected to: History
taking, clinical examination for manifestations of sepsis. Complete blood
count, differential leucocytic count, C- reactive protein, Blood culture,
Random blood sugar, and determination of RDW % were done to all
neonates.
Results: Our study showed that the mean RDW % was higher among cases
than controls (16.4 ± 3.8 and 13.7± 1.6 respectively) (P = 0.001), with
further increase in preterm neonates. Also, there was a significant negative
correlation (P=0.007) between RDW level and age of neonate, and that
RDW increases when RBS increased (p=0.05), but there was a statistically
significant positive correlation (p=0.001) between RDW and Griffin score.
However, there was insignificant difference between RDW and WBCs or I/T
ratio. Morever, blood culture was positive in 63.3% of cases only. Also,
CRP was high in 76.7% of cases and 30% of controls (P=0.01).
Conclusion: RDW % can serve as a marker and prognostic indicator in
neonatal sepsis especially when used together with Griffin score.
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