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العنوان
Epicardial fat thickness , plasma von willbrand factor and neutrphil to lymphocyte ratio in acute ischemic /
المؤلف
Matar, Eman Samy.
هيئة الاعداد
باحث / إيمان سامي مطر
مشرف / وفيق محمود الشيخ
مشرف / إبراهيم السيد الأحمر
مشرف / جيلان محمود محمد علي
الموضوع
Cerebral ischemia.
تاريخ النشر
2019.
عدد الصفحات
115 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب النفسي والصحة العقلية
تاريخ الإجازة
3/4/2019
مكان الإجازة
جامعة المنوفية - كلية الطب - الامراض العصبية
الفهرس
Only 14 pages are availabe for public view

from 138

from 138

Abstract

Epicardial fat thickness is generally identified as the echo-free space between the outer wall of the myocardium and the visceral layer of pericardium and is measured perpendicularly on the free wall of the right ventricle at end-systole. Echocardiographic epicardial fat thickness normally ranges from a minimum of 1 mm to a maximum of 4 mm. Echocardiographic epicardial fat thickness correlates with metabolic syndrome, insulin resistance, coronary artery disease, and subclinical atherosclerosis, and therefore it might serve as a simple tool for cardiometabolic risk prediction.
Inflammation plays a significant role in the pathogenesis of ischemic stroke and its mechanism is complex. Both pro-inflammatory and anti-inflammatory mediators are involved in the pathogenesis of ischemic stroke, an imbalance of which leads to inflammation
Neutrophils are the first type of leucocytes to infiltrate ischemic brain (30 min to a few hours of focal cerebral ischemia), peak earlier (Days 1–3), and then disappear or decrease rapidly with time, their existence is largely masked after 3 days by large-scale accumulation of activated microglia/macrophages in the inflammatory site. The neutrophil-to-lymphocyte ratio (NLR) parameter was reported to be an important measure of systemic inflammation. However NLR has not been fully investigated as useful biomarkers of diagnosis in patients with cerebral infarction.
Von Willebrand Factor (VWF) is a blood multimeric glycoprotein involved in hemostasis. VWF plays a major role in blood