الفهرس 
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Abstract
This study aimed to evaluate clinical presentation and outcomes of active tuberculosis in diabetic patients to help planning better national TB management programs. It included all patients with tuberculosis admitted to El-Mahalla Chest Hospital during the period from Jan 2014 to Dec 2016.
Inclusion criteria:
All forms of active TB cases which admitted to El-Mahalla Chest Hospital during the period from Jan 2014 to Dec 2016were included in the study.
The included patients were be divided into two groups :
group (1): Tuberculous patients with diabetes mellitus.
group (2): Tuberculous patients without diabetes mellitus.
Exclusion criteria: 1. Cases with incomplete information. 2. Patients aged less than 15 years old.
3. Patients with other underlying diseases that might influence the immune status as HIV, HCV, MDR, cancer and rheumatoid arthritis
It was found that:
There was no statistically significant difference between the two groups regarding sex, smoking and blood biochemistry.
The mean age was significantly higher in group 1 (54.14 ± 11.40) compared to group 2 (36.93 ± 15.02).
Body weight is significantly higher in diabetics compared to nondiabetic patients.
There was no statistically significant difference between the two groups regarding the type of tuberculosis.
Old TB cases constituted 14.2% of the total studied patients & new TB cases were 85.7%. Old cases of TB were significantly higher in group 1.
In this study, co-morbidities are significantly higher in diabetics than nondiabetic patients (48.9 % versus 15.4%).
The percentage of positive in baseline sputum smear ZN in pulmonary TB cases was higher in diabetic patients compared to nondiabetic patients (77.5% versus 71%).
After 2nd and 6th months of treatment, the percentage of positive sputum ZN smear in pulmonary TB cases were higher in diabetic patients compared to nondiabetic patients.
According to the distribution of lesion in chest x-ray atypical radiological localization of TB is more frequently have seen in diabetics compared with non-diabetics.
According to the type of lesion in chest x-ray tuberculous patients with diabetes mellitus presented with atypical lesion with a wider range of pulmonary infiltration. Cavitary images have seen more in diabetic patients compared than nondiabetic patients (32.7% versus 13.7%)
More extensive TB disease on CXRs compared with non-diabetic patients.
Almost tuberculous patients with diabetes mellitus in this study had a favorable outcome but most of the diabetic patients had prolonged time for treatment from tuberculosis more than 6 months than nondiabetic and the number of died patients with diabetes more than nondiabetic patients (4 cases versus 3 cases).
Complications showed a statistically significant difference between the two groups. 34.3% of tuberculous patients with diabetes mellitus were complicated by delayed conversion of sputum compared to 29.6% nondiabetic patients.
There was no statistically significant difference between diabetic groups regarding the type of tuberculosis, radiology, and outcome of treatment.