الفهرس 
Transient Tachypnea of the NewbornOnly 14 pages are availabe for public view
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Abstract
Introduction: Prostaglandins may be given about one hour before an elective caesarean section after excluding the presence of contraindication to their use to decrease the neonatal respiratory diseases and thus, the number of children who suffered from bronchopulmonary dysplasia that occurs frequently in children who had previously TTN will diminish Aim: The aim of this study is to assess the efficacy of Prostaglandin E1 on the reduction of the neonatal respiratory morbidity in diabetic women scheduled for elective caesarean section. Patients and Methods: This is a Randomized Controlled Trial which was conducted on pregnant diabetic women who were approached before elective caesarean section, managed in Ain Shams University Maternity Hospital, and their neonates followed up in the Neonatal Intensive Care Unit to assess the effect of misoprostol when given for diabetic women one hour before their scheduled caesarean section upon reducing the neonatal respiratory morbidity, The study population comprises (60) pregnant diabetic women, fulfilling the inclusion criteria, during the study period. Results: Although RD was higher in placebo group (30% vs. 13.3%), the difference did not reach to a statistical significant level. Similarly, Need for MV (Nasal tube/ MV) was lower in the treatment group (30% vs. 13.3%), the difference did not reach to a statistical significant level, There was a borderline significant difference between both groups as regard NICU admission (10% vs. 30%). Conclusion: In our trial, we use Misoprostol that is given vaginally to diabetic women one hour before term elective caesarean section between 37-37+6 weeks compared to placebo, it simulates the normal labour to enable the neonate through catecholamines surge, and thus surfactant secretion for better adaptation to the extrauterine life and that is noted after excluding any significant difference in age, weight, gravidity, parity, medical history, surgical history, pulse, blood pressure, gestational age, through a statistically less significant difference appearing in a better Apgar scores at 5 minutes, less neonatal respiratory morbidities and especially TTN, less NICU admission less fetal mortality from the placebo group without noting any side effect in mothers or neonates