الفهرس 
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Abstract
The results of this study showed changes in ER and PR expression with disease progression from primary tumor to nodal metastasis.
Although the percentage of cases with hormonal receptor changes and more importantly cases changing from negative to positive are statistically insignificant, yet still warrant attention as a treatment modality modifier.
Prediction of nodal metastasis hormonal receptors results from the profile of the primary tumor is considered inappropriate.
Explanation of hormonal therapy failure may be attributed to negativity of hormonal receptors in nodal metastasis.
A subset of patients may benefit endocrine therapy, despite ER negativity in both tumor and nodes, PR assessment is the key to this benefit.