الفهرس 
Acknowledgement
Clinical presentation of gliomaOnly 14 pages are availabe for public view
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Abstract
Early and accurate diagnosis of brain gliomas is important for better outcomes. CT & MRI are considered the primary imaging modalities of choice, however they can’t sometimes differentiates residual/recurrent tumors from radiation induced injuries.Radionuclide imaging with thalium-201, 99mTc- tetrofosmin, and 99mTc sesta MIBI were used for evaluation of gliomas.Currently PET is the most effective diagnostic tool for distinguishing recurrent/residual glioma from radiation necrosis but it is expensive and not widely available in all centers.
Our study evaluates the role of Tc-99m DMSA (V) SPECT/CT scan in detecting residual/recurrent tumors from gliosis in glioma’s patients postreatment. Thirty seven patients were enrolled in this study; 23 males (57.5%) and 17 females (42.5%) with mean age of 39.6+/- 2.5.According to the presence or absence of DMSA (V) uptake our patients were divided into two groups; the positive group included 17 cases all of them proven to be true positive either by biopsy or by clinical/ neuroimaging follow up and the negative group which included 20 cases; only 2 of them were false negative due to the small size of the tumor (<1 cm), while the rest of cases proven to be true negative.Quantitative analysis of DMSA (V) SPECT/CT scan expressed in the form of early and delayed L/N uptake ratios and were higher in case of viable tumor tissue i.e. residual or recurrenced.