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العنوان
comparison between two optical coherence tomography devices in the evaluation of corneal opacities/
المؤلف
Ibrahim, Doaa Tag Eldin Mohamed.
هيئة الاعداد
مشرف / دعاء تاج الدين محمد ابراهيم
مشرف / محمود حسن مرسى
مشرف / علاء عاطف غيث
مشرف / يونس السعيد عبد الحافظ
الموضوع
Ophthalmology.
تاريخ النشر
2019.
عدد الصفحات
P 52. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
تاريخ الإجازة
18/5/2019
مكان الإجازة
جامعة الاسكندريه - كلية الطب - ophthalmology
الفهرس
Only 14 pages are availabe for public view

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from 64

Abstract

Anterior segment OCT is a relatively new technology opening new horizons in precise visualization and objective assessment of anterior segment structures
These devices are becoming essential and indispensable tools for better diagnosis and treatment of anterior segment diseases including corneal disorders, cataract, glaucoma, and even disorders of the lacrimal system.
Currently there are multiple OCT machines built on the spectral domain technology as the Cirrus™ HD-OCT Model 5000 AS-OCT (Carl Zeiss Meditec, Inc. Dublin, CA) which carries out 27,000 A-scans/sec with an axial resolution of 5 µm and the Heidelberg Spectralis® HRA AS-OCT which takes 40,000 A-scans/sec and has a depth resolution of 5 µm. Both devices are not only capable of posterior segment imaging, but also anterior segment imaging as well.
The main idea of the current study was to validate the corneal opacity depth using two spectral domain optical coherence tomography devices in order to make right treatment and surgical decisions
The aim of the current work was to compare between two spectral domain optical coherence tomography devices regarding their assessment of corneal opacity depth and central corneal thickness namely the Cirrus™ HD-OCT Model 5000 AS-OCT (Carl Zeiss Meditec, Inc. Dublin, CA) and the Heidelberg Spectralis® HRA AS-OCT (Heidelberg Engineering, Heidelberg Germany).
The current study was carried on 20 patients, 6 of them were males (30%) and 14 were females (70%). One eye was tested for each patient. The age of the study population ranged from 4 years to 70 years and the mean age was 35.85 years ± 21.82 years. Moreover, 11 eyes were right eyes (55.0%) and 9 eyes were left eyes (45.0%).
Regarding the location of the corneal opacity, the position of corneal opacity was central in 18 of the studied eyes (90 %) and paracentral in only 2 eyes (10 %).
The Student’s t-test was used to compare between the two devices regarding depth of corneal opacity measurements and it revealed no statistically significant differences. The Intra class Correlation coefficient was 0.983 denoting high agreement between the two devices.
Moreover, the Bland Altman plot demonstrated high agreement between the two anterior segment OCT devices, meaning that the two devices can be used interchangeably.
The Student’s t-test was used to compare between the two devices regarding central corneal thickness measurement and it revealed no statistically significant differences between the central corneal thickness measurements of the two devices. The Intra class Correlation coefficient was 0.999 denoting high agreement between the two devices.
Moreover, the Bland Altman plot demonstrated high agreement between the two anterior segment OCT devices, meaning that the two d