الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
The study was conducted on 130 patients with gallstone disease who underwent laparoscopic cholecystectomy at Alexandria Main University Hospital during the period from March 2018 till October 2018.
The study included 30 males (23.1%) and 100 females (76.9%), with a mean age of 44.38 years ± 15.54. Sixty-five patients (50%) of our study had positive family history of gallstones. Most of our female patients had a history of parity (87%). However, only 34 % of female patients declared a history of using oral contraceptive pills (OCP). Mean BMI of the studied patients was 30.9 kg/m2 ± 5.5. Analysis of our data revealed that only one case (0.7%) had a normal BMI while the other 129 patients (99.3%) were overweight and obese. In view of comorbidities, 15.4% were diabetics while 28.5% were hypertensives and 5.4% were dyslipidaemic. Only 21.5% had a previous history of surgical interventions. Elevated total serum cholesterol level was observed in 29.2% while elevated TG level was detected in17.7%. Abnormally decreased HDL-C was detected in 14.6% while abnormally elevated serum level of LDL-C was detected in 16.2%.
According to the type of gallstones, patients were divided into 2 groups: 101 patients (77.7%) in Cholesterol gallstones group and 29 patients (22.3%) in pigment gallstones group.
Female predominance was observed in both groups with no statistically significant difference. Statistically significant higher age in pigment gallstones groups was detected (mean 52.14±16.81 years, p=0.002) while cholesterol gallstones group had a statistically significant higher BMI (mean 31.31±5.79 Kg/m2, p=0.024). Presence of comorbidities other than DM, HTN and dyslipidaemia was significantly higher in pigment gallstones group
(p= 0.048) with having cardiac disease was the most significant (p= 0.035).
A single patient with a normal BMI (22 kg/m2) was included. This case was a diabetic female -aged 43 years- with a history of parity. She had neither family history of gallstones, nor a history of using oral contraceptive pills or other comorbidities. She had mildly elevated serum cholesterol level (205 mg/dl). She had a single pigment gallstone.
Overweight male patients had a significantl