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Abstract Epilepsy is a common neurological disorder in the pediatric age group. It is a disorder characterized by the occurrence of at least 2 unprovoked seizures. Epilepsy remains one of the most common neurological disorders encountered in clinical practice. Epilepsy affects about 50 million people worldwide. Its incidence is highest among young children. Intractable (Drug-resistant) epilepsy is failure of adequate trials of two (or more) tolerated, appropriately chosen and used antiepileptic drug (AED) schedules (whether as mono therapies or in combination) to achieve sustained seizure freedom. The patients categorized as intractable when they developed at least 1 seizure or more per month in a 6-month period despite being treated with at least 2 antiepileptic drugs. About 70% of patients have controlled seizures with antiepileptic drugs (AED), and about 25% of the patients with epilepsy don‘t have any significant improvement in the reduction of the amount of seizures even when two or three AED are used. The aim of our work was to determine the etiology and outcome of intractable convulsion in children and risk factor of intractability and factors related to poor outcome. The study was carried out upon 100 infant and children classified as follow: group I (Intractable epilepsy group): Fifty patients with intractable epilepsy were studied (18 males and 32 females). |